María Angélica Bravo Núñez
Beyond the lab: The variable landscape of genomic instability in yeast isolates
Dr María Angélica Bravo Núñez is an Assistant Professor at Cornell, where her lab studies the evolution and molecular mechanisms of chromosome segregation in yeasts. She earned her PhD at the Stowers Institute for Medical Research under Dr Sarah Zanders, where she studied the wtf family of meiotic drivers in fission yeast. She then completed her postdoctoral training in Dr Andrew Murray’s lab at Harvard University, where she uncovered links between meiotic gene expression and adaptive genome instability. Her current research focuses on non-canonical mode of chromosome segregation and the consequences of such processes to evolution. Dr Bravo Núñez’s work has been recognized with numerous honors, including the DeLill Nasser Award from the Genetics Society of America and an HHMI Hanna H Gray Fellowship.
Micha Fridman
Chemical probes in antifungal research: Decoding mechanisms, resistance, and drug discovery concepts
Professor Micha Fridman is a faculty member of the School of Chemistry at Tel Aviv University. His research focuses on the development and mechanistic understanding of antimicrobial agents, with a particular emphasis on antibiotics and antifungal compounds. By integrating organic chemistry, microbiology, and molecular biology, his work addresses drug resistance and aims to improve therapeutic efficacy. He received his BA, MSc, and PhD in chemistry from the Technion – Israel Institute of Technology, followed by postdoctoral research at Harvard University in chemical biology and medicinal chemistry. He joined Tel Aviv University in 2008, where he established an interdisciplinary research program at the interface of chemistry and biology, focusing on microbial systems, antibiotic resistance mechanisms, and the design of novel bioactive molecules. His research group pioneered the development of fluorescent antifungal probes, enabling realtime visualization of drug action and resistance in live cells. This work has provided new insights into intracellular drug targeting and fungal defense mechanisms, contributing to the broader effort to combat antimicrobial resistance.
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