Research projects

We help to progress high-quality translational research across our theme areas, addressing the most pressing health issues for our communities


Showing 27 research projects

Developing novel screening strategies to identify modulators of microglial cell states


Understanding the brain’s immune cells to help develop treatments for people with Alzheimer’s disease.

Using whole genome sequencing to identify non-coding elements associated with common, complex phenotypes

Genetics and Genomics

Understanding the role in disease development of the non-coding genome to help improve treatments

Releasing a critical bottleneck in Pneumocystis research

Clinical mycology

Using an innovative approach to progress research into a deadly human pathogen and develop new treatments

Analysis of extracellular vesicle cargo as biomarkers to differentiate Alzheimer’s disease and dementia with Lewy bodies


Understanding and tracking changes in the brain during neurodegeneration to help improve treatments

Investigating the aetiology of non-autoimmune young-onset diabetes in sub-Saharan Africa.


Understanding the causes of an unusual form of diabetes in young people in sub-Saharan Africa

Establishing the role of fungal infection in potentiating Alzheimer’s Disease risk

Clinical mycology


Understanding possible triggers of Alzheimer’s Disease to help improve treatments

Personalised Pulmonary Rehabilitation: Harnessing the power of Cardiopulmonary Exercise Testing (CPET)


Improving care for ageing patients with chronic respiratory disease

Identification of novel therapeutic targets for TDP-43 proteinopathies


Improving therapies for neurodegenerative diseases

Commensal Fungi in the Lung: Innocent Bystanders or Pathogenic Orchestrators of Severe Asthma?

Clinical mycology

Investigating the relationship between the lung microbiome and severe asthma

Developing a Novel Genomic Biomarker for the Early Detection of Neurodegeneration


Improving early diagnosis of neurodegenerative disease

Cryptococcus-Mycobacterium interactions: Framework for a co-infection model

Clinical mycology

Investigating the effects of co-infection of Cryptococcus and Mycobacterium on patients

Mind The Gap: Steps towards precision rehabilitation in chronic pain


Using VR technology to understand the neurobiological mechanisms of chronic pain to develop effective treatments