Luke is a scientist in the AGE (Ageing & long-term conditions, Genetics, & Epidemiology) group in the Department of Clinical & Biomedical Sciences at the University of Exeter. His research interests closely align to the NIHR Exeter BRC: his research is focussed on understanding why some people are more susceptible than others for risk of age-related, long-term chronic conditions. This includes lifespan overall, multimorbidity, pharmacogenetics, and specific biological mechanisms (e.g., iron). With improved understanding of mechanisms and risk factors leading to disease susceptibility, we can inform interventions and personalised medicine.
Luke has a human genetics and bioinformatics background that he combines with epidemiological training and collaboration with clinical and interdisciplinary colleagues to address these questions, utilizing cohort data with combined genetics, healthcare records, and biomarkers. He is a keen advocate of reproducible and open science; see his GitHub repository here.
Research projects that Luke has been involved in
Genetics and Genomics
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