Ailsa is a postdoctoral research fellow in Nick Owens’ lab. Ailsa’s work with the BRC focuses on understanding the genomic regulation of human pancreatic development to help to understand rare and common pancreatic diseases.
Ailsa’s research leverages a unique collection of human fetal pancreatic tissue, enabling the investigation of dynamic changes to gene expression which occur across pancreatic development. Ailsa employs advanced sequencing techniques, particularly Oxford Nanopore Technologies long-read sequencing to generate deep, high-resolution insights into gene expression regulation. By integrating developmental biology with cutting edge genomics, Ailsa aims to understand the role of gene regulation in development and how this can impact disease risk later in life.
In parallel to her work within the BRC, Ailsa is also utilising a novel sequencing methodology to understand how regulatory sequences of the genome control gene expression and how changes in these sequences lead to disease.
Research projects that Ailsa has been involved in
Diabetes
Genetics and Genomics
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