Katie’s research will develop and identify targeted therapeutic avenues for diabetes treatment using a novel human cell model of hormone secretion. Her research will involve using human choroid plexus epithelial cells (ChPEC) as another possible source of insulin and islet protective factors in diabetes. This will expand previous novel data which demonstrated insulin production from ChPEC cells in the brain.
Katie’s previous research focused on therapeutically activating a metabolic energy sensor in the pancreatic alpha cell by using new pharmaceuticals.
More recently, a secured Society for Endocrinology (SfE) Early Career grant focused on the optimisation of hormone secretion from a new human primary alpha cell line.