Showing 27 research projects
Platform for Online Recruitment, Triage and Assessment for Brain Health Research (Brain Health PORTAL)
Neurodegeneration
Creating a new digital resource for brain health research in adults
The VITAL Study
Neurodegeneration
Assessing at-home blood testing to help detect Alzheimer’s and related diseases in older adults.
Using brain cells to treat diabetes
Diabetes
Exploring the role of insulin and islet protection factors released from stem cell derived neural cells to help improve treatment for diabetes
Assessing Cancer Predisposition in UK and Iceland Populations using whole genome sequencing
Genetics and Genomics
Using large genomic datasets to evaluate the impact of pathogenic genetic variants on a person’s likelihood of developing cancer
Antifungal drug delivery in a 3D infection microenvironment
Clinical mycology
Improving treatment for fungal infections
Discovering novel genes and pathomechanisms underlying rare neurodevelopmental disorders in Pakistan
Genetics and Genomics
Understanding how genes cause rare brain disorders in Pakistan
Is BCG immunisation resulting in protective immune responses against fungal pathogens?
Clinical mycology
Researching whether BCG vaccination helps to prevent fungal infections
Whole genome sequencing to identify cis and trans regulators of the proteome
Genetics and Genomics
Identifying genetic variants associated with levels of proteins circulating in blood
Drug Repurposing in Neonatal Diabetes Study
Diabetes
Investigating the effect of an existing medicine on people with neonatal diabetes
Developing a protocol to isolate motor neurons from post-mortem brains for molecular profiling
Neurodegeneration
Improving DNA testing for neurodegenerative diseases
Using Magnetic Resonance Imaging to investigate Glymphatic System alterations in Clinically Isolated Syndrome
Neurodegeneration
Understanding the role of the Glymphatic System in Multiple Sclerosis
Cardiovascular disease in the context of multiple long-term conditions and frailty
Rehabilitation
Using hospital data to improve treatment of older people with cardiovascular disease